Prevalence of macrolide resistance in Treponema pallidum is associated with macrolide consumption
نویسندگان
چکیده
منابع مشابه
Treponema pallidum macrolide resistance in BC.
Since mid-1997 British Columbia has experienced an outbreak of syphilis, initially in heterosexuals and more recently among men who have sex with men (MSM). Starting in 1999, primarily in patients presenting to the sexually transmitted diseases clinic at the BC Centre for Disease Control (BCCDC), moist lesions of primary and secondary syphilis were swabbed for polymerase chain reaction (PCR) te...
متن کاملTwo mutations associated with macrolide resistance in Treponema pallidum in Shandong, China.
Zhen Li, Jianling Hou, Rongtao Zheng, Zhongwei Li, Jing Wen, Dianchang Liu, Ruyuan Liu, Tongsheng Chu, Bing Liu, Gongqi Yu, Hongqing Tian, FuRen Zhang Shandong Provincial Institute of Dermatology and Venereology, Provincial Academy of Medical Science, Jinan, Shandong, China; Shandong Provincial Hospital for Skin Diseases, Jinan, Shandong, China; Shandong Provincial Medical Center for Dermatoven...
متن کاملMacrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains
BACKGROUND High rates of 23S rDNA mutations implicated in macrolide resistance have been identified in Treponema pallidum samples from syphilis patients in many countries. Nonetheless, some clinicians have been reluctant to abandon azithromycin as a treatment for syphilis, citing the lack of a causal association between these mutations and clinical evidence of drug resistance. Although azithrom...
متن کاملPrevalence of clindamycin-resistant Staphylococcus aureus induced by macrolide resistance
Introduction: Since the incidence of various infections caused by Staphylococcus aureus increases, the use of effective antibiotics such as clindamycin has been growing to treat the systemic and local infections caused by such organisms. Antibiotic-resistant species are emerging and spreading in today's communities due to misuse of antibiotics and incomplete treatment, turning into a serious ch...
متن کاملHigh prevalence of macrolide resistant Treponema pallidum strains in a London centre.
OBJECTIVES Macrolide resistant Treponema pallidum strains, caused by mutations in the 23S ribosomal RNA (23S rRNA) gene, are widespread and increasingly prevalent. The authors aimed to establish the strain types of T pallidum isolated from patients in a London sexual health centre and to determine the frequency of macrolide resistance. METHODS T pallidum DNA from blood and ulcer samples were ...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 2019
ISSN: 0022-2615,1473-5644
DOI: 10.1099/jmm.0.000885